Presently, mechanistic paradigms in catalysis generally posit that the active species remains either homogeneous or heterogeneous throughout the reaction. In this work, we show that a prominent industrial process, palladium (Pd)–catalyzed vinyl acetate ...
Exogenous messenger RNAs (mRNAs) require cellular machinery for delivery and translation but also encounter inhibitory factors. To investigate their regulation, we performed genome-wide CRISPR screens with in vitro–transcribed mRNAs in lipid ...
Insects dominate animal species diversity yet face many threats from anthropogenic drivers of change. Many features of insect ecology make them a challenging group, and the fragmented state of knowledge compromises our ability to make general statements ...
Light-sheet fluorescence microscopy has revolutionized biology by visualizing dynamic cellular processes in three dimensions. However, light scattering in thick tissue and photobleaching of fluorescent reporters limit this method to studying thin or ...
Microbial life has dominated Earth’s history but left a sparse fossil record, greatly hindering our understanding of evolution in deep time. However, bacterial metabolism has left signatures in the geochemical record, most conspicuously the Great ...
Human high-order thalamic nuclei activity is known to closely correlate with conscious states. However, it is not clear how those thalamic nuclei and thalamocortical interactions directly contribute to the transient process of human conscious perception. ...
Researchers’ failures to communicate are jeopardizing even basic tests, but new projects may point the way forward
The latest in science and policy
Benchmarks must be established and progress tracked to set a global target and take action
Homogeneous and heterogeneous catalysis work concurrently in a chemical process
Programmable RNA sensor and molecular tools refine therapeutic payload production
Loss of biodiversity threatens the study of tool use and other cultural behaviors in animals
How acoustically levitating a diamond enabled a redesign of biotech automation
Living cells that produce biofuel; robots that assist factory workers; intelligent machines that guide drug discovery—these technologies are “deep” in that they achieve something extraordinary—often thought impossible—and push society forward. Indeed, so-...
A historian probes the origins and evolution of psychological manipulation
The artificial intelligence (AI) debate is increasingly polarized in Africa, mirroring a trend across the globe. On one side, utopian headlines, such as “5 Ways To Harness AI And End Poverty Forever,” claim that AI will revolutionize development. On the ...
HomeScienceVol. 388, No. 6742Science safeguardsBack To Vol. 388, No. 6742 Full accessLetterNextGen Voices Share on Science safeguardsZhen Wang [email protected], Sara Shakir [email protected], [...] , Bram Servais [email protected], Safaa Osman [email protected], [...] , Yutong Hu [email protected], Yumna Gamal [email protected], Malk Elshrief [email protected], Karen Jacqueline Cloete [email pro…
Editors’ selections from the current scientific literature
Bile acid metabolism meets glucagon-like peptide 1 signaling in osteoarthritis
A microbe from the Dead Sea switches to a tissue-like form when compressed
Rebuilding muscle through the power of mRNA binding protein therapeutics
Study is the first to show an animal combining different calls to make new meanings
A new book offers advice for mentoring those who do not aspire to follow in faculty’s footsteps
Ancient DNA sheds light on a fleeting, lush interlude of North African prehistory
Multiple companies aim to generate power by corraling plasma with twisted magnets
Opposition to Trump administration and fears of customs run-ins are shifting travel plans
DOGE argues killing grants saves money, but a Science analysis suggests more than $1.4 billion in sunk research costs may produce few results
The reasons aren’t clear—and the agency’s director claims the president’s policies haven’t slowed grant awards
Grant terminations halt research on improving vaccinations and preventing future pandemics