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Tales of Traveling Tau: Is Transfer Between Neurons Normal? 27 Aug 2013 | 10:00 am

Is transfer of tau from one neuron to the next a normal activity, hijacked by pathogenic protein in the case of tauopathies?

Expansions in ataxin-2 can lead to either ALS or spinocerebellar ataxia—even in the same family, according to a new pedigree from New York.

Two studies examine factors that heighten the risk for dementia in type 2 diabetes patients. Both highlight depression as a dangerous comorbidity.

Studies support the idea that mitochondrial changes drive aging and AD pathogenesis.

A parkinsonism-associated ubiquitin ligase interacts with parkin to promote mitophagy.

Researchers identified a genetic variant in the microglial gene CD33 that protects against Alzheimer’s.

Alzheimer’s and prion disease may be linked through an α-secretase.

The route to early dementia starts in adolescence, with low cognitive function and alcohol intoxication as major predictors.

Studies reported at AAIC demonstrate that biomarkers help predict who will develop cognitive impairment and dementia.

AD but no Amyloidβ? Researchers at AAIC 2013 theorized on the pathology underlying this form of dementia.