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The Transparency Imperative 20 Aug 2013 | 05:00 am
The Affordable Care Act made preliminary efforts to collect and disseminate data on health care price, utilization, and quality in the United States. This commentary proposes that all such data need t...
Invasive Meningococcal Disease in Men Who Have Sex With Men 20 Aug 2013 | 05:00 am
This commentary discusses the New York City Department of Health and Mental Hygiene's recommendation for meningococcal vaccination for all men who have sex with men in New York City who have had intim...
Are Human Genes Patentable? 20 Aug 2013 | 05:00 am
This commentary reviews the events leading to the Supreme Court decision regarding Myriad Genetics patents on the BRCA1 and BRCA2 genes. Those developing molecular diagnostics will have to comport wit...
Primary Care Interventions to Prevent Child Maltreatment: U.S. Preventive Services Task Force Recommendation Statement 20 Aug 2013 | 05:00 am
Chinese translation Description: Update of the child abuse and neglect portion of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation statement on screening for family and intimate pa...
Handling of Rescue and Missing Data Affects Synthesis and Interpretation of Evidence: The Sodium–Glucose Cotransporter 2 Inhibitor Example 20 Aug 2013 | 05:00 am
Confidence in evidence summarized in meta-analyses depends on the strength of the underlying studies. This inherent limitation of syntheses appears in the case of a meta-analysis of sodium–glucose cot...
Sodium–Glucose Cotransporter 2 Inhibitors for Type 2 Diabetes A Systematic Review and Meta-analysis 20 Aug 2013 | 05:00 am
Background: Sodium–glucose cotransporter 2 (SGLT2) inhibitors are a new class of antidiabetic drugs. Purpose: To assess the efficacy and safety of SGLT2 inhibitors in adults with type 2 diabetes. Data...
Comparative Effectiveness of New Oral Anticoagulants and Standard Thromboprophylaxis in Patients Having Total Hip or Knee Replacement A Systematic Rev... 20 Aug 2013 | 05:00 am
Background: Pharmacologic thromboprophylaxis reduces the risk for venous thromboembolism after total hip replacement (THR) or total knee replacement (TKR). New oral anticoagulants (NOACs), including d...
Tofacitinib in Combination With Nonbiologic Disease-Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis A Randomized Trial 20 Aug 2013 | 05:00 am
Chinese translation Background: Many patients with rheumatoid arthritis (RA) do not achieve adequate and safe responses with disease-modifying antirheumatic drugs (DMARDs). Tofacitinib is a novel, ora...
Blood Pressure and Mortality in U.S. Veterans With Chronic Kidney Disease A Cohort Study 20 Aug 2013 | 05:00 am
Chinese translation Background: The ideal blood pressure (BP) to decrease mortality rates in patients with non–dialysis-dependent chronic kidney disease (CKD) is unclear. Objective: To assess the asso...
A Home-Based Intervention to Reduce Depressive Symptoms and Improve Quality of Life in Older African Americans A Randomized Trial 20 Aug 2013 | 05:00 am
Chinese translation Background: Effective care models for treating older African Americans with depressive symptoms are needed. Objective: To determine whether a home-based intervention alleviates dep...
