Editorial Board [Masthead] 27 Jul 2013 | 12:00 am

Fungus-Specific Sirtuin HstD Coordinates Secondary Metabolism and Development through Control of LaeA [Articles] 27 Jul 2013 | 12:00 am

The sirtuins are members of the NAD+-dependent histone deacetylase family that contribute to various cellular functions that affect aging, disease, and cancer development in metazoans. However, the ph...

The Plasma Membrane Proton Pump PMA-1 Is Incorporated into Distal Parts of the Hyphae Independently of the Spitzenkorper in Neurospora crassa [Article... 27 Jul 2013 | 12:00 am

Most models for fungal growth have proposed a directional traffic of secretory vesicles to the hyphal apex, where they temporarily aggregate at the Spitzenkörper before they fuse with the plasma membr...

Spatial Reorganization of Saccharomyces cerevisiae Enolase To Alter Carbon Metabolism under Hypoxia [Articles] 27 Jul 2013 | 12:00 am

Hypoxia has critical effects on the physiology of organisms. In the yeast Saccharomyces cerevisiae, glycolytic enzymes, including enolase (Eno2p), formed cellular foci under hypoxia. Here, we investig...

Candida albicans Forms a Specialized "Sexual" as Well as "Pathogenic" Biofilm [Articles] 27 Jul 2013 | 12:00 am

Candida albicans forms two types of biofilm in RPMI 1640 medium, depending upon the configuration of the mating type locus. In the prevalent a/α configuration, cells form a biofilm that is impermeable...

Active Hydrocarbon Biosynthesis and Accumulation in a Green Alga, Botryococcus braunii (Race A) [Articles] 27 Jul 2013 | 12:00 am

Among oleaginous microalgae, the colonial green alga Botryococcus braunii accumulates especially large quantities of hydrocarbons. This accumulation may be achieved more by storage of lipids in the ex...

Mutual Cross Talk between the Regulators Hac1 of the Unfolded Protein Response and Gcn4 of the General Amino Acid Control of Saccharomyces cerevisiae ... 27 Jul 2013 | 12:00 am

Hac1 is the activator of the cellular response to the accumulation of unfolded proteins in the endoplasmic reticulum. Hac1 function requires the activity of Gcn4, which mainly acts as a regulator of t...

Unisexual Reproduction Enhances Fungal Competitiveness by Promoting Habitat Exploration via Hyphal Growth and Sporulation [Articles] 27 Jul 2013 | 12:00 am

Unisexual reproduction is a novel homothallic sexual cycle recently discovered in both ascomycetous and basidiomycetous pathogenic fungi. It is a form of selfing that induces the yeast-to-hyphal dimor...

Articles of Significant Interest Selected from This Issue by the Editors [Spotlight] 27 Jul 2013 | 12:00 am

Histidine Phosphotransfer Proteins in Fungal Two-Component Signal Transduction Pathways [Minireviews] 27 Jul 2013 | 12:00 am

The histidine phosphotransfer (HPt) protein Ypd1 is an important participant in the Saccharomyces cerevisiae multistep two-component signal transduction pathway and, unlike the expanded histidine kina...