This Month's Highlights 31 Jul 2013 | 10:00 pm

An Expanding Universe of FSGS Genes and Phenotypes: LMX1B Mutations Cause Familial Autosomal Dominant FSGS Lacking Extrarenal Manifestations 31 Jul 2013 | 10:00 pm

Maintaining Mitochondrial Morphology in AKI: Looks Matter 31 Jul 2013 | 10:00 pm

Vascular Access for Hemodialysis in Older Adults: A "Patient First" Approach 31 Jul 2013 | 10:00 pm

Can Genetics Risk-Stratify Patients with Membranous Nephropathy? 31 Jul 2013 | 10:00 pm

Estimation of Glomerular Podocyte Number: A Selection of Valid Methods 31 Jul 2013 | 10:00 pm

The podocyte depletion hypothesis has emerged as an important unifying concept in glomerular pathology. The estimation of podocyte number is therefore often a critical component of studies of progress...

AKI in an HIV Patient 31 Jul 2013 | 10:00 pm

The renal manifestations of patients infected with HIV are diverse. Patients may have podocytopathies ranging from a minimal-change–type lesions to FSGS or collapsing glomerulopathy. Furthermore, such...

Deletion of the Insulin Receptor in the Proximal Tubule Promotes Hyperglycemia 31 Jul 2013 | 10:00 pm

Nearly all renal tubular epithelial cells express insulin receptor. The insulin receptor in the distal tubule appears to modulate BP, but the role of the insulin receptor in the proximal tubule is unk...

LMX1B Mutations Cause Hereditary FSGS without Extrarenal Involvement 31 Jul 2013 | 10:00 pm

LMX1B encodes a homeodomain-containing transcription factor that is essential during development. Mutations in LMX1B cause nail-patella syndrome, characterized by dysplasia of the patellae, nails, and...

Laminin {beta}2 Gene Missense Mutation Produces Endoplasmic Reticulum Stress in Podocytes 31 Jul 2013 | 10:00 pm

Mutations in the laminin β2 gene (LAMB2) cause Pierson syndrome, a severe congenital nephrotic syndrome with ocular and neurologic defects. LAMB2 is a component of the laminin-521 (α5β21) trimer, an i...