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Hightlights from this issue 5 Aug 2013 | 01:17 pm
Lumianl GI Overall burden of Helicobacter pylori on mortality H pylori colonisation has been associated with increased risk of peptic ulcer disease and gastric cancer, and reduced risk of asthma and...
Update from EIC 2013 5 Aug 2013 | 01:17 pm
<sec> <p>It gives me great pleasure to provide you with a quick update on our journal. In June this year the 2012 impact factors were announced and ours increased to 10.732 (2011 IF 10.111), the highe...
Beyond scoring: a modern interpretation of disease progression in chronic liver disease 5 Aug 2013 | 01:17 pm
Introduction The progressive understanding of the natural history of chronic liver diseases (CLD) and the relative pathophysiological mechanisms have led to important improvements in the current mana...
Viral evolution in chronic hepatitis B: a branched way to HBeAg seroconversion and disease progression? 5 Aug 2013 | 01:17 pm
Evolution is a natural event that enables the animal and plant kingdoms to adapt and survive to changing environmental effects. The same evolutionary pressures also help to shape micro-organisms, incl...
Antifibrotic therapy in pancreatic diseases 5 Aug 2013 | 01:17 pm
In the current study by Ishiwatari et al, a novel antifibrotic therapy has been shown to revert pancreatic fibrosis induced by dibutyltin dichloride and cerulein in rats. 1 The authors have previously...
From genetic association studies to the biology of interleukin-28B in hepatitis C virus infection and beyond 5 Aug 2013 | 01:17 pm
Numerous studies have confirmed and extended the striking results of independent genome-wide association studies showing that single nucleotide polymorphisms (SNPs) near the IL28B gene (encoding inter...
Efficacy and safety of lesogaberan in gastro-oesophageal reflux disease: a randomised controlled trial 5 Aug 2013 | 01:17 pm
Objective Lesogaberan (AZD3355) is a novel -aminobutyric acid B-type receptor agonist designed to treat gastro-oesophageal reflux disease (GERD) by inhibiting transient lower oesophageal sphincter re...
In vivo evaluation of acid-induced changes in oesophageal mucosa integrity and sensitivity in non-erosive reflux disease 5 Aug 2013 | 01:17 pm
Objective Patients with non-erosive reflux disease (NERD) have impaired oesophageal mucosal integrity (dilated intercellular spaces). Oesophageal mucosal integrity reflects the balance between repeat...
Association between Helicobacter pylori and mortality in the NHANES III study 5 Aug 2013 | 01:17 pm
Objective Persistent colonisation by Helicobacter pylori, and especially by cagA-positive strains, has been related to several health outcomes with effects in opposite directions. Thus, it is importa...
Correction 5 Aug 2013 | 01:17 pm
W J Tee, G Chan, Z Ahmed, et al. 40: INPATIENT ENDOSCOPY: REFERRAL APPROPRIATENESS AND EFFICIENCY OF SERVICE PROVISION. Gut 2013;62(Suppl 2):A17-A18. doi:10.1136/gutjnl-2013-305143.40. The author list...
