Endocrinology-journals - erc.endocrinology-journals.org - Endocrine Related Cancer current issue
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IL6 sensitizes prostate cancer to the antiproliferative effect of IFN{alpha}2 through IRF9 23 Aug 2013 | 06:48 pm
Development and progression of prostate cancer (PCa) are associated with chronic inflammation. The cytokine interleukin 6 (IL6) can influence progression, differentiation, survival, and angiogenesis o...
The management of head-and-neck paragangliomas 23 Aug 2013 | 06:48 pm
Paragangliomas (PGLs) are tumours originating from neural crest-derived cells situated in the region of the autonomic nervous system ganglia. Head-and-neck PGLs (HNPGLs) originate from the sympathetic...
Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment 23 Aug 2013 | 06:48 pm
Mesenchymal stem cells (MSCs) have an inherent tropism for sites of inflammation, which are frequently present in sites of cancer, including prostatic lesions. MSCs have been defined as CD73/CD90/CD10...
MicroRNAs in the tumour microenvironment: big role for small players 23 Aug 2013 | 06:48 pm
MicroRNAs (miRNAs) represent a class of small non-coding RNAs with an important regulatory role in various physiological processes as well as in several pathologies including cancers. It is noteworthy...
Evaluating vaspin and adiponectin in postmenopausal women with endometrial cancer 21 Aug 2013 | 08:29 pm
Insulin resistance is a well-documented risk factor for the development of endometrial cancer. Adiponectin and vaspin are insulin-sensitizing proteins that are secreted from adipose tissue. A clear as...
Targeting mTOR in RET mutant medullary and differentiated thyroid cancer cells 21 Aug 2013 | 08:29 pm
Inhibitors of RET, a tyrosine kinase receptor encoded by a gene that is frequently mutated in medullary thyroid cancer, have emerged as promising novel therapies for the disease. Rapalogs and other ma...
The optimal use of cardiac imaging in the quantification of carcinoid heart disease 19 Aug 2013 | 04:34 pm
Carcinoid heart disease is a rare cause of right-sided valvular dysfunction, primarily mediated by serotonin. It is an important complication in patients with carcinoid syndrome and occurs in 20–50% o...
Thyroid dysfunction and tyrosine kinase inhibitors in renal cell carcinoma 19 Aug 2013 | 04:34 pm
The most recent World Health Organization classification of renal neoplasms encompassed nearly 50 distinctive renal neoplasms. Different histological subtypes have different clinical outcomes and show...
Common gene pathways and families altered by DNA methylation in breast and prostate cancers 19 Aug 2013 | 04:34 pm
Epigenetic modifications, such as DNA methylation, are widely studied in cancer as they are stable and easy to measure genome wide. DNA methylation changes have been used to differentiate benign from ...
IGF2 revs the steroidogenesis engine 19 Aug 2013 | 04:34 pm
Molecular understanding of how prostate cancers evade hormone therapy greatly increased over the last several years, and the realization that de novo steroidogenesis plays a significant role in tumor ...
