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The Effective Add Inherent in 2-Zone Negative Lenses Inhibits Eye Growth in Myopic Young Chicks [Physiology and Pharmacology] 31 Jul 2012 | 10:26 pm
Purpose. We investigated the effects on refractive development and ocular growth of 2-zone concentric lenses with different negative powers in each of the optical zones, in normal and myopic eyes in ...
{beta}-LGND2, an ER{beta} Selective Agonist, Inhibits Pathologic Retinal Neovascularization [Physiology/Pharmacology] 31 Jul 2012 | 10:26 pm
Purpose. The goal of our study was to evaluate the in vitro and in vivo anti-angiogenic effects of ERβ selective agonist, β-LGND2, using human retinal microvascular endothelial cell (HRMVEC) cultures...
Myopia Control with Orthokeratology Contact Lenses in Spain: Refractive and Biometric Changes [Clinical and Epidemiologic Research] 31 Jul 2012 | 10:26 pm
Purpose. To compare axial length growth between white children with myopia wearing orthokeratology contact lenses (OK) and distance single-vision spectacles (SV) over a 2-year period. Methods. Subj...
iTRAQ Quantitative Proteomics in the Analysis of Tears in Dry Eye Patients [Cornea] 31 Jul 2012 | 10:26 pm
Purpose. We analyzed the change in protein expression of tear film proteins in dry eye (DE) and non-DE (NDE) patients using isobaric tag for relative and absolute quantitation (iTRAQ) technology. Me...
Structure-Function Relationship of the Macular Visual Field Sensitivity and the Ganglion Cell Complex Thickness in Glaucoma [Glaucoma] 31 Jul 2012 | 10:26 pm
Purpose. We attempted to understand better the relationship between the macular visual field (VF) mean sensitivity (MS) assessed by standard automated perimetry (SAP) and the ganglion cell complex th...
Changes in Mouse Corneal Epithelial Innervation with Age [Cornea] 28 Jul 2012 | 06:10 am
Purpose. We defined the quantitative changes in corneal epithelial nerve fibers during mouse development. Methods. Corneal whole mounts from 36 mice were immunostained with a specific anti-β-III tu...
SERPINA3K Protects against Oxidative Stress via Modulating ROS Generation/Degradation and KEAP1-NRF2 Pathway in the Corneal Epithelium [Cornea] 28 Jul 2012 | 06:10 am
Purpose. We recently reported that SERPINA3K (SA3K), a member of the serine proteinase inhibitor (SERPIN) family, has antiangiogenic and anti-inflammatory activities. Here we investigated the antioxi...
Effects of Proinflammatory Cytokines on the Claudin-19 Rich Tight Junctions of Human Retinal Pigment Epithelium [Retinal Cell Biology] 28 Jul 2012 | 06:10 am
Purpose. Chronic, subclinical inflammation contributes to the pathogenesis of several ocular diseases, including age-related macular degeneration. Proinflammatory cytokines affect tight junctions in ...
Corneal Biomechanical Properties from Two-Dimensional Corneal Flap Extensiometry: Application to UV-Riboflavin Cross-Linking [Cornea] 28 Jul 2012 | 06:10 am
Purpose. Corneal biomechanical properties are usually measured by strip extensiometry or inflation methods. We developed a two-dimensional (2D) flap extensiometry technique, combining the advantages ...
Genetic Factors for Choroidal Neovascularization Associated with High Myopia [Genetics] 28 Jul 2012 | 06:10 am
Purpose. Nonsyndromic high myopia, defined by a refractive error greater than –6 diopters (D), is associated with an increased risk of macular choroidal neovascularization (CNV), a vision-threatening...
