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Fate of TLR-1/TLR-2 agonist functionalised pDNA nanoparticles upon deposition at the human bronchial epithelium in vitro 21 Aug 2013 | 05:00 am
Background: Plasmid DNA vaccination is a promising approach, but studies in non-human primates and humans failed to achieve protective immunity. To optimise this technology further with focus on pulmo...
Quantum dots incorporated magnetic nanoparticles for imaging colon carcinoma cells 17 Aug 2013 | 05:00 am
Background: Engineered multifunctional nanoparticles (NPs) have made a tremendous impact on the biomedical sciences, with advances in imaging, sensing and bioseparation. In particular, the combination...
Characterization of structural stability of palm oil esters-based nanocosmeceuticals loaded with tocotrienol 1 Aug 2013 | 05:00 am
Background: Palm oil esters (POEs) are esters derived from palm oil and oleyl alcohol have great potential in the cosmetic and pharmaceutical industries due to the excellent wetting behavior of the es...
Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle 19 Jul 2013 | 05:00 am
Interaction of nanoparticles with proteins is the basis of nanoparticle bio-reactivity. This interaction gives rise to the formation of a dynamic nanoparticle-protein corona. The protein corona may in...
Investigating bioconjugation by atomic force microscopy 15 Jul 2013 | 05:00 am
Nanotechnological applications increasingly exploit the selectivity and processivity of biological molecules. Integration of biomolecules such as proteins or DNA into nano-systems typically requires t...
Fibril-mediated oligomerization of pilin-derived protein nanotubes 5 Jul 2013 | 05:00 am
Background: Self-assembling protein nanotubes (PNTs) are an intriguing alternative to carbon nanotubes for applications in bionanotechnology, in part due to greater inherent biocompatibility. The type...
Correction: potential therapeutic application of gold nanoparticles in B-chronic lymphocytic leukemia (BCLL): enhancing apoptosis 1 Jul 2013 | 05:00 am
After the publication of this work [1], it was brought to our attention that there might have been an error during compilation of the gel bands in Figure 5. We regret such unintentional errors and any...
The effect of ultrasound-related stimuli on cell viability in microfluidic channels 28 Jun 2013 | 05:00 am
Background: In ultrasonic micro-devices, contrast agent micro-bubbles are known to initiate cavitation and streaming local to cells, potentially compromising cell viability. Here we investigate the ef...
Schlieren visualization of ultrasonic standing waves in mm- sized chambers for ultrasonic particle manipulation 28 Jun 2013 | 05:00 am
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Elastomeric microparticles for acoustic mediated bioseparations 28 Jun 2013 | 05:00 am
Background: Acoustophoresis has been utilized successfully in applications including cell trapping, focusing, and purification. One current limitation of acoustophoresis for cell sorting is the relian...
