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T-cell homeostasis in pediatric multiple sclerosis: Old cells in young patients 27 Aug 2013 | 12:45 am
Objective: To assess pediatric patients with multiple sclerosis (MS) for early signs of homeostatic and functional abnormalities in conventional (Tcon) and regulatory T cells (Treg). Methods: We st...
Attention following stroke 27 Aug 2013 | 12:45 am
Deficits of attention frequently accompany brain damage. An article in this issue of Neurology®1 provides evidence that a computerized measure may help the clinician to determine which aspects of atte...
Decisional capacity in cognitively impaired patients with Parkinson disease 27 Aug 2013 | 12:45 am
Decline in complex abilities is a crucial early clinical dimension of neurodegenerative diseases such as Alzheimer dementia (AD)1–3 and Parkinson disease (PD),4,5 and of their prodromal states such as...
Premature immune senescence in children with MS: Too young to go steady 27 Aug 2013 | 12:45 am
The common view in the field of multiple sclerosis (MS) is that immune-mediated attacks of the CNS reflect some imbalance between effector and regulatory limbs of the immune system. Studies in adults ...
Spotlight on the August 27 Issue 27 Aug 2013 | 12:45 am
The ability to consent to Parkinson disease research 27 Aug 2013 | 12:45 am
This issue of Neurology® includes an article by Karlawish et al.1 on giving consent to be part of Parkinson disease (PD) research. People with PD often want to help doctors and scientists learn more a...
Teaching NeuroImages: Sarcoidosis presenting as longitudinally extensive myelitis: Excellent response to infliximab 27 Aug 2013 | 12:45 am
A 44-year-old man presented following 2 weeks of progressive right body numbness, weakness, and circumferential burning sensation around his trunk. MRI spine demonstrated longitudinally extensive myel...
Teaching Video NeuroImages: Hollenhorst plaque 27 Aug 2013 | 12:45 am
A 73-year-old man with hypertension and hyperlipidemia was seen in clinic complaining of decreased vision in his right eye. Bedside examination demonstrated a right eye inferior lateral visual field d...
Clinical Reasoning: A 35-year-old woman with acute seizures and behavior change 27 Aug 2013 | 12:45 am
A previously healthy 35-year-old Sudanese woman was admitted with new-onset right hemispheric seizures with secondary generalization. The patient’s vital signs were temperature 100.2°F, blood pressure...
