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Incident lacunes preferentially localize to the edge of white matter hyperintensities: insights into the pathophysiology of cerebral small vessel dise... 27 Aug 2013 | 05:50 pm
White matter hyperintensities and lacunes are among the most frequent abnormalities on brain magnetic resonance imaging. They are commonly related to cerebral small vessel disease and associated with ...
Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study 27 Aug 2013 | 05:50 pm
Elevated plasma total homocysteine is associated with increased risk of dementia/Alzheimer’s disease, but underlying pathophysiological mechanisms are not fully understood. This study investigated pos...
Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre 27 Aug 2013 | 05:50 pm
Cerebrovascular disease and vascular risk factors are associated with Alzheimer’s disease, but the evidence for their association with other neurodegenerative disorders is limited. Therefore, we compa...
Inflammatory components in human Alzheimer's disease and after active amyloid-{beta}42 immunization 27 Aug 2013 | 05:50 pm
Inflammatory processes are important in the pathogenesis of Alzheimer’s disease and in response to amyloid-β immunotherapy. We investigated the expression of multiple inflammatory markers in the brain...
Natural killer cells and their receptors in multiple sclerosis 27 Aug 2013 | 05:50 pm
The immune system has crucial roles in the pathogenesis of multiple sclerosis. While the adaptive immune cell subsets, T and B cells, have been the main focus of immunological research in multiple scl...
