Oxfordjournals - cardiovascres.oxfordjournals.org
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Differential changes in titin domain phosphorylation increase myofilament stiffness in failing human hearts 19 Aug 2013 | 09:17 pm
Aims Titin-based myofilament stiffness is defined by the expression levels of the cardiac titin-isoforms, N2B and N2BA, and by phosphorylation of the elastic titin domains N2-B unique sequence (N2-Bu...
Efficacy of epicardially delivered adipose stroma cell sheets in dilated cardiomyopathy 19 Aug 2013 | 09:17 pm
Aims Few studies have assessed the effects of cell therapy in non-ischaemic cardiomyopathies which, however, contribute to a large number of cardiac failures. Assuming that such conditions are best s...
Response gene to complement 32 deficiency causes impaired placental angiogenesis in mice 19 Aug 2013 | 09:17 pm
Aims The objectives of this study are to determine the role of response gene to complement 32 (RGC-32) in the placental angiogenesis during pregnancy and explore the underlying mechanisms. Methods a...
Effects of peroxisome proliferator-activated receptor-{beta} activation in endothelin-dependent hypertension 19 Aug 2013 | 09:17 pm
Aims We analysed the chronic effects of the peroxisome proliferator-activated receptor β/ (PPAR-β) agonist GW0742 on the renin-independent hypertension induced by deoxycorticosterone acetate (DOCA)-s...
Functional remodelling of arterial endothelium during early postnatal development in rats 19 Aug 2013 | 09:17 pm
Aims Functional remodelling takes place permanently in the circulatory system. Whether this process also affects the anti-contractile effect of the endothelium during vasoconstrictor action is unknow...
The arrhythmogenic consequences of increasing late INa in the cardiomyocyte 19 Aug 2013 | 09:17 pm
This review presents the roles of cardiac sodium channel NaV1.5 late current (late INa) in generation of arrhythmic activity. The assumption of the authors is that proper Na+ channel function is neces...
