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Prenatal nicotine exposure enhances the trigeminocardiac reflex via serotonin receptor facilitation in brainstem pathways 15 Aug 2013 | 09:01 pm
In this study we used a rat model for prenatal nicotine exposure to test whether clinically relevant concentrations of brain nicotine and cotinine are passed from dams exposed to nicotine to her pups,...
In anesthetized pigs human chorionic gonadotropin increases myocardial perfusion and function through a {beta}-adrenergic-related pathway and nitric o... 15 Aug 2013 | 09:01 pm
Human chorionic gonadotropin (hCG) is not only responsible for numerous pregnancy-related processes, but can affect the cardiovascular system as well. So far, however, information about any direct eff...
Can tidal breathing with deep inspirations of intact airways create sustained bronchoprotection or bronchodilation? 15 Aug 2013 | 09:01 pm
Fluctuating forces imposed on the airway smooth muscle due to breathing are believed to regulate hyperresponsiveness in vivo. However, recent animal and human isolated airway studies have shown that t...
Contribution of nitric oxide in the contraction-induced rapid vasodilation in young and older adults 15 Aug 2013 | 09:01 pm
We tested the hypothesis that reduced nitric oxide (NO) bioavailability contributes to the attenuated peak and total vasodilation following single-muscle contractions in older adults. Young (n = 10; 2...
Contrasting effects of fatigue on multifinger coordination in young and older adults 15 Aug 2013 | 09:01 pm
We investigated the effects of fatigue produced by timed maximal voluntary contraction (MVC) of the index finger of the right hand on performance in MVC and accurate cyclic force production tasks in r...
Ankle morphology amplifies calcaneus movement relative to triceps surae muscle shortening 15 Aug 2013 | 09:01 pm
The present study investigated the mechanical role of the dorsoventral curvature of the Achilles tendon in the conversion of the shortening of the plantarflexor muscles into ankle joint rotation. Dyna...
Obesity accentuates circadian variability in breathing during sleep in mice but does not predispose to apnea 15 Aug 2013 | 09:01 pm
Obesity is a primary risk factor for the development of obstructive sleep apnea in humans, but the impact of obesity on central sleep apnea is less clear. Given the comorbidities associated with obesi...
Effect of airway control by glottal structures on postural stability 15 Aug 2013 | 09:01 pm
Maintenance of upright posture involves complex neuromotor processes that include control of thoracic and abdominal pressures. Control of airflow by glottal structures is a primary determinant of thor...
Does hypercapnia-induced impairment of cerebral autoregulation affect neurovascular coupling? A functional TCD study 15 Aug 2013 | 09:01 pm
Neurovascular coupling (NVC) and dynamic cerebral autoregulation (dCA) are both impaired in the acute phase of ischemic stroke, but their reciprocal interactions are difficult to predict. To clarify t...
Potassium dynamics are attenuated in hyperkalemia and a determinant of QT adaptation in exercising hemodialysis patients 15 Aug 2013 | 09:01 pm
Disturbances in plasma potassium concentration (pK) are well known risk factors for the development of cardiac arrhythmia. The aims of the present study were to evaluate the effect of hemodialysis on ...
