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Klotz, Epstein criteria for active surveillance and actual surgical outcomes 27 Aug 2013 | 04:11 pm
There is no broad agreement agreement (yet) across the prostate cancer community about acceptable “standard” criteria for eligibility for active surveillance as a form of first-line management of low-...
Abiraterone acetate or enzalutamide first? It seems to matter for some patients 26 Aug 2013 | 04:42 pm
In a commentary on May 29 this year we noted that the activity of abiraterone acetate + prednisone following docetaxel-based chemotherapy and enzalutamide therapy seemed to be lower than after only do...
Significant new trials for men with high-risk or advanced forms of prostate cancer 25 Aug 2013 | 09:37 pm
The following is basic information on five relatively recently initiated or planned new trials for the treatment of men with high-risk or advanced forms of cancer, together with links to more detail o...
Flawed PSA test provides inaccurate results in Pennsylvania 23 Aug 2013 | 10:01 pm
We’ve said it before. We’ll say it again. And now there’s an even better reason to take the message seriously. … A single, slightly elevated PSA test result is rarely a good reason to rush off and get...
Does shift work really increase risk for clinically significant prostate cancer? 23 Aug 2013 | 08:15 pm
So the longer we go on using the PSA test as a primary tool for the assessment of risk for prostate cancer, the more we learn about what the test results may — or more importantly may not — actually b...
PSA testing, life and health insurance, and full disclosure 22 Aug 2013 | 11:22 pm
Many readers of this blog quite certainly have strong opinions about the position of the American Cancer Society (ACS) on use of the PSA test in assessment of risk for prostate cancer. However, one do...
Does “penile rehabilitation” really work? 22 Aug 2013 | 05:31 pm
A new review in BJU International looks carefully at the evidence for use of phosphodiesterase type 5 (PDE5) inhibitors (e.g., Viagra and Cialis), prostaglandins, and vacuum erection devices in “penil...
Bimagrumab (BMY338) as a potential treatment for cancer-related cachexia 22 Aug 2013 | 01:03 am
It is worthy of note that FDA has just granted “breakthrough therapy” to an investigational drug called bimagrumab for the treatment of a rare muscle-wasting disease known as sporadic inclusion body m...
The end of a futile quest in management of localized prostate cancer? 21 Aug 2013 | 06:22 pm
Over the years, it has proved almost impossible to recruit patients to comparative trials of different types of first-line treatment in the management of localized prostate cancer — particularly in th...
What is what you “survived” wasn’t really … 20 Aug 2013 | 06:10 pm
For those who are interested, there’s a very readable article on the Bloomberg web site today entitled “What if what you ’survived’ wasn’t cancer?” The author expands on the idea that we might want to...
