Sciencemag - stke.sciencemag.org
General Information:
Latest News:
Database of Cell Signaling 30 Nov -0001 | 12:00 am
Epidermal Growth Factor Receptor Pathway
[Research Article] The Rho Exchange Factors Vav2 and Vav3 Control a Lung Metastasis-Specific Transcriptional Program in Breast Cancer Cells 30 Nov -0001 | 12:00 am
Two Vav isoforms could be targeted to prevent breast tumors from metastasizing to the lung.
[Research Article] An Interaction Between BZR1 and DELLAs Mediates Direct Signaling Crosstalk Between Brassinosteroids and Gibberellins in Arabidopsis 30 Nov -0001 | 12:00 am
Crosstalk between two signaling pathways that control plant growth occurs through the DELLA family of transcription factors.
[Perspective] Rho GEFs and Cancer: Linking Gene Expression and Metastatic Dissemination 30 Nov -0001 | 12:00 am
The guanine exchange factors Vav2 and Vav3 regulate gene expression to promote the metastasis of breast tumors to the lung.
[Perspective] HCN1 Channels: A New Therapeutic Target for Depressive Disorders? 30 Nov -0001 | 12:00 am
Reduced function of hyperpolarization-activated cyclic nucleotide-gated channels alleviates depressive-like behavior in rodents.
[Perspective] Inflammatory Factors Contribute to Depression and Its Comorbid Conditions 30 Nov -0001 | 12:00 am
Manipulation of pro- and anti-inflammatory mediators may improve treatments for depression.
[Presentation] Circadian Rhythms of Glucocorticoid Hormone Actions in Target Tissues: Potential Clinical Implications. 30 Nov -0001 | 12:00 am
The circadian clock cooperates with the hypothalamic-pituitary-adrenal axis to control tissue sensitivity to diurnally fluctuating circulating glucocorticoids.
[Presentation] Primary Generalized Glucocorticoid Resistance and Hypersensitivity: The End-Organ Involvement in the Stress Response 30 Nov -0001 | 12:00 am
Distinct activities of glucocorticoid receptor variants and isoforms should be considered in the management of pathologic conditions treated with glucocorticoids.
[Editors' Choice] Targeting TRPV4 to Treat Metabolic Disease 30 Nov -0001 | 12:00 am
Antagonism of TRPV4 channels contributes to the browning of white adipose tissue.
Database of Cell Signaling 30 Nov -0001 | 12:00 am
Brassinosteroid Signaling Pathway
