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ActiTarg Series - Targeted Libraries timtec.com 11 Jun 2010 | 05:20 am
Molecules in targeted libraries possess cumulative structural characteristics common to known Nuclear Receptors and GPCR Ligands, Ion Channel and Kinase Modulators, Protease and Serpins Inhibitors. Mo...
ActiTarg Series - Targeted Libraries timtec.net 11 Jun 2010 | 05:20 am
Molecules in targeted libraries possess cumulative structural characteristics common to known Nuclear Receptors and GPCR Ligands, Ion Channel and Kinase Modulators, Protease and Serpins Inhibitors. Mo...
Alternative Splicing of the TRPC3 Ion Channel Calmodulin/IP3 Receptor-Binding Domain in the Hindbrain Enhances Cation Flux neuro.cjb.net 16 Aug 2012 | 12:01 am
Canonical transient receptor potential (TRPC3) nonselective cation channels are effectors of G-protein-coupled receptors (GPCRs), activated via phospholipase C–diacylglycerol signaling. In cerebellar ...
Topography of Native SK Channels Revealed by Force Nanoscopy in Living Neurons neuro.cjb.net 16 Aug 2012 | 12:01 am
The spatial distribution of ion channels is an important determinant of neuronal excitability. However, there are currently no quantitative techniques to map endogenous ion channels with single-channe...
AAQ chemical can reportedly restore sight to blind mice techgeer.com 27 Jul 2012 | 04:24 am
AAQ is based on a photoswitch that binds to protein ion channels on the surface of retinal cells. The chemical is called AAQ and it works by making the blind cells in the retina sensitive to light. (m...
Proceedings of the National Academy of Sciences USA online: August 8, 2013 newswire.rockefeller.edu 9 Aug 2013 | 02:51 am
Proceedings of the National Academy of Sciences USA online: August 8, 2013 UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 ...
Water molecules control inactivation and recovery of potassium channels uchospitals.edu 29 Jul 2013 | 10:00 pm
Just 12 molecules of water cause the long post-activation recovery period required by potassium ion channels before they can function again.
Open and shut: a breakthrough discovery on the slow inactivating K+ channel gate isgtw.org 21 Aug 2013 | 04:04 pm
Ion channels regulate electrical currents, many of which are primary to the body’s biological processes. Like tiny faucets, these channels open and close in response to signals, but the ways in which ...
PhD in Biophysics, Department of Biochemistry & Biophysics, Stockholm University, Sweden jobcqr.com 27 Aug 2013 | 02:01 pm
Project title: Electrophysiology & Modeling of Ligand-gated Ion Channels Membrane proteins are critical for signaling and transport across membranes, but these processes cannot be accomplished with st...
Spike statistics and coding properties of phase models from ion channels to neural coding edoc.hu-berlin.de 27 Aug 2013 | 11:45 am
Ziel dieser Arbeit ist es eine Beziehung zwischen den biophysikalischen Eigenschaften der Nervenmembran, und den ausgeführten Berechnungen und Filtereigenschaften eines tonisch feuernden Neurons, unt...
