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Apparent Argatroban Resistance in a Patient with Elevated Factor VIII Levels 8 Jul 2013 | 07:00 pm

OBJECTIVE: To report a case in which there was a lack of activated partial thromboplastin time (aPTT) correlation with plasma argatroban concentrations in a patient with elevated factor VIII levels wh...

Linezolid Desensitization for a Patient with Multiple Medication Hypersensitivity Reactions 8 Jul 2013 | 07:00 pm

OBJECTIVE: To describe a case in which a linezolid desensitization protocol was successfully used for a polymicrobial surgical wound infection in a patient with multiple drug hypersensitivity reaction...

Reintroduction of Clozapine After Perforation of the Large Intestine--A Case Report and Review of the Literature 8 Jul 2013 | 07:00 pm

OBJECTIVE: To report on a patient who was successfully rechallenged with clozapine after perforation of the large intestine and pulmonary embolism post operatively, and provide a literature review on ...

Occurrence of Milnacipran-Associated Morbilliform Rash and Serotonin Toxicity 8 Jul 2013 | 07:00 pm

OBJECTIVE: To report the development of morbilliform rash and serotonin toxicity after the addition of milnacipran to a patient’s medication therapy. CASE SUMMARY: A 57-year-old white female presente...

Cholestatic Jaundice as a Result of Combination Designer Supplement Ingestion 8 Jul 2013 | 07:00 pm

OBJECTIVE: To report a case of cholestatic jaundice as a result of combination herbal and designer supplement use. CASE SUMMARY: A 50-year-old Hispanic male presented to the hospital with a 1-week hi...

Tremors and Agitation Following Low-Dose Intravenous Hydromorphone Administration in a Patient with Kidney Dysfunction 8 Jul 2013 | 07:00 pm

OBJECTIVE: To report a case of tremors and agitation associated with the administration of low doses of intravenous hydromorphone in a patient with acute kidney injury in the setting of chronic kidney...

Impact of Severe Hypothyroidism on Cyclophosphamide Disposition and Routes of Metabolism and Transport in a Patient with Treatment-Resistant Lupus Nep... 8 Jul 2013 | 07:00 pm

OBJECTIVE: To report what we believe to be the first case of severe hypothyroidism with reduced drug metabolism and transport activity. CASE SUMMARY: A 32-year-old African American woman with a histo...

Efficacy and Safety of Mirtazapine in Fibromyalgia Syndrome Patients: A Randomized Placebo-Controlled Pilot Study 8 Jul 2013 | 07:00 pm

BACKGROUND: Data from an open-label trial suggest that mirtazapine might prove useful in treatment of fibromyalgia syndrome (FMS). OBJECTIVE: To obtain preliminary efficacy data of mirtazapine for es...

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