Ucsd - thebrainobservatory.ucsd.edu - The Brain Observatory
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Not-So-White Matter 17 Jun 2010 | 03:42 am
Not-So-White Matter Postmortem MR imaging has revealed widespread deep White Matter pathology localized primarily in the frontal lobes. Histopathological staining will elucidate the nature of the abn...
70 Microns 17 Jun 2010 | 03:41 am
70 Microns Section thickness determines the total number of slices and it is an extremely important parameter for subsequent histo-pathological staining and analysis. read more
Welcome to Project H.M. 17 Jun 2010 | 03:40 am
Welcome to Project H.M. We believe that the enormous attention that was devoted to patient H.M. when he was living and generously served as a keen research subject ought to be matched by a similarly ...
Project H.M. Phase 2 Overview 17 Jun 2010 | 03:39 am
Project H.M. Phase 2 Overview Once the collection of tissue slices from the brain of patient H.M. was safely archived cryo-genically, the work towards reconstructing a neurological picture of the cas...
Blockface Imaging 17 Jun 2010 | 03:38 am
Blockface Imaging Histological sections are going to be stored cryogenically in serial order. We have set the goal to acquire an image of the specimen’s blockface before each section is collected. To...
The WHOLE Brain 17 Jun 2010 | 03:37 am
The WHOLE Brain The decision to cut the brain as one single block was taken on account of the fact that gross dissection of the sample into smaller blocks or thick slabs to be processed separately am...
So Cryo Baby, Cryo 17 Jun 2010 | 03:34 am
So Cryo Baby, Cryo As the brain of Patient H.M. was cut, histological slices were being collected in serial order in 36-well compartment boxes containing 0.1 M phosphate buffer solution. The next ste...
Project H.M. Questions and Answers 17 Jun 2010 | 03:26 am
Project H.M. Questions and Answers We have received many inquiries regarding our methods during and after the cutting of the brain of patient H.M. that occurred from December 2nd through December 4th...
Brodmann Revisited 17 Jun 2010 | 03:24 am
Brodmann Revisited The Eye Institute of the National Institute of Health sponsors a new map of the cortical surface, starting from the back of the brain... read more
California Streamin' 17 Jun 2010 | 03:21 am
California Streamin' The Brain Observatory used several web cameras to invite the general public to participate in an extraordinary scientific endeavor. Researchers voyaged through the brain of the m...