Adiposity and Insulin Resistance in Humans: The Role of the Different Tissue and Cellular Lipid Depots 6 Aug 2013 | 10:00 pm

Human adiposity has long been associated with insulin resistance and increased cardiovascular risk, and abdominal adiposity is considered particularly adverse. Intra-abdominal fat is associated with i...

New Insights Into the Role of Sequestosome 1/p62 Mutant Proteins in the Pathogenesis of Paget's Disease of Bone 6 Aug 2013 | 10:00 pm

Paget's disease of bone (PDB) is characterized by focal areas of aberrant and excessive bone turnover, specifically increased bone resorption and disorganized bone formation. Germline mutations in the...

11{beta}-Hydroxysteroid Dehydrogenase 1: Translational and Therapeutic Aspects 6 Aug 2013 | 10:00 pm

11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) interconverts the inactive glucocorticoid cortisone and its active form cortisol. It is widely expressed and, although bidirectional, in vivo it func...

Thyroid Hormone Signaling and Homeostasis During Aging 6 Aug 2013 | 10:00 pm

Studies in humans and in animal models show negative correlations between thyroid hormone (TH) levels and longevity. TH signaling is implicated in maintaining and integrating metabolic homeostasis at ...

Translational Highlights from The Endocrine Society Journals 6 Aug 2013 | 10:00 pm

The Endocrine Society Laureate Awards 6 Aug 2013 | 10:00 pm

The Endocrine Society 2013 Laureate Awards 6 Aug 2013 | 10:00 pm

Translational Highlights from The Endocrine Society Journals 30 May 2013 | 10:00 pm

The Role of Estrogens in Control of Energy Balance and Glucose Homeostasis 30 May 2013 | 10:00 pm

Estrogens play a fundamental role in the physiology of the reproductive, cardiovascular, skeletal, and central nervous systems. In this report, we review the literature in both rodents and humans on t...

Molecular Characteristics of Malignant Ovarian Germ Cell Tumors and Comparison With Testicular Counterparts: Implications for Pathogenesis 30 May 2013 | 10:00 pm

This review focuses on the molecular characteristics and development of rare malignant ovarian germ cell tumors (mOGCTs). We provide an overview of the genomic aberrations assessed by ploidy, cytogene...