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Triple-Negative Breast Cancers: Associations Between Imaging and Pathological Findings for Triple-Negative Tumors Compared With Hormone Receptor-Posit... 24 Jul 2013 | 01:40 am
Purpose. Triple-negative (TN) breast cancers have high malignancy potential and are often characterized by early systemic relapse. Early detection is vital, but there are few comprehensive imaging re...
Health-Related Quality of Life With Adjuvant Docetaxel- and Trastuzumab-Based Regimens in Patients with Node-Positive and High-Risk Node-Negative, HER... 24 Jul 2013 | 01:40 am
Background. This study aims to describe and compare health-related quality of life (HRQL) in patients with node-positive and high-risk node-negative HER2-positive early breast cancer receiving adjuva...
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Cell - A PLETHORA-Auxin Transcription Module Controls Cell Division Plane Rotation through MAP65 and CLASP pubup.org 19 Apr 2012 | 01:34 pm
This article presents a good example of delicate and complex regulatory networks that determine the direction of cell division in stem cells of plants. Although a large number of transcription factors...
[Biochemistry] Structural and Functional Properties of Platelet-Derived Growth Factor and Stem Cell Factor Receptors cshperspectives.cshlp.org 1 Aug 2013 | 06:00 pm
The receptors for platelet-derived growth factor (PDGF) and stem cell factor (SCF) are members of the type III class of PTK receptors, which are characterized by five Ig-like domains extracellularly a...
Multiple coagulation factor deficiency protein 2 contains the ability to support stem cell self-renewal [Research Communications] fasebj.org 1 Aug 2013 | 12:01 pm
Defects in multiple coagulation factor deficiency protein 2 (MCFD2) are a cause of factor V and factor VIII combined deficiency type 2 (F5F8D). MCFD2 was also suggested to play an important role as an...
Pseudogene OCT4-pg4 functions as a natural micro RNA sponge to regulate OCT4 expression by competing for miR-145 in hepatocellular carcinoma carcin.oxfordjournals.org 2 Aug 2013 | 02:28 pm
The POU transcription factor OCT4 is a pleiotropic regulator of gene expression in embryonic stem cells. Recent studies demonstrated that OCT4 is aberrantly expressed in multiple types of human cancer...
Amplified NKG2C+ NK Cells in Cytomegalovirus (CMV) Infection Preferentially Express Killer Cell Ig-like Receptor 2DL: Functional Impact in Controlling... jimmunol.org 21 Aug 2013 | 01:02 am
CMV infection represents a major complication in hematopoietic stem cell transplantation, which compromises graft outcome. Downregulation of HLA class I expression is one mechanism by which CMV evades...
Engineering Stem Cells: Microparticles Create Localized Control of Stem Cell Differentiation and Reduce Growth Factor Use gtresearchnews.gatech.edu 10 Jul 2013 | 06:57 pm
Before scientists and engineers can realize the dream of using stem cells to create replacements for worn out organs and battle damaged body parts, they’ll have to develop ways to grow complex three-d...
Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning content.jci.org 30 Nov -0001 | 12:00 am
The transcription factor GATA-2 plays vital roles in quite diverse developmental programs, including hematopoietic stem cell (HSC) survival and proliferation. We previously identified a vascular endot...
“Helper cells” improve survival rate of transplanted stem cells, mouse study finds sciguru.com 27 Aug 2013 | 08:44 pm
Like volunteers handing out cups of energy drinks to marathon runners, specially engineered “helper cells” transplanted along with stem cells can dole out growth factors to increase the stem cells’ en...
Cell Wall Pectic Arabinans Influence the Mechanical Properties of Arabidopsis thaliana Inflorescence Stems and Their Response to Mechanical Stress pcp.oxfordjournals.org 1 Aug 2013 | 11:01 am
Little is known of the dynamics of plant cell wall matrix polysaccharides in response to the impact of mechanical stress on plant organs. The capacity of the imposition of a mechanical stress (periodi...
